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Tohoku Univ. Technology :High brightness fluorescent calcium sensor:T20-1178_T20-1180_T20-1182_T20-1183_T21-303

Useful for elucidating various biological mechanisms involving calcium ions

The inventors have previously developed G-CaMP and R-CaMP (CaMP) as proteinaceous fluorescent calcium sensors. By introducing CaMP into a cell, the location of the cell can be identified and changes in calcium ion concentration can be observed as changes in CaMP fluorescence intensity. ・G-CaMP7, G-CaMP7.09: Displays green fluorescence. ・R-CaMP1.07: Displays red fluorescence and can be used in combination with the photo-stimulation probe Channelrhodopsin-2, which is commonly used for cell function manipulation.

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